One in eight couples has trouble conceiving. Do you know how many of the cases are caused by unexplained male infertility? Nearly a quarter. For years, scientists have known that infertility can be linked to sperm that fail to throw out histones from DNA during development, but the reasons for this failure and how it happens is unclear. Now, however, that lack of clarity may be changing.
Promising new research out of Penn Medicine is showing the precise location of the retained histones and the key gene that regulates them. Researchers have also created a mouse model with a mutated version of the gene. This allows investigators to track the defects in sperm, starting with the early stages of sperm development and going through fertilization. This research could lead us to a better understanding of infertility in men, and how epigenetic mutations are passed to future generations.
What does it mean, when sperm fail to evict histones? Histones are the main proteins in chromatin. Their function is to package DNA and turn genes on and off. Healthy sperm lose about 90-95 percent of these proteins, replacing them with protamines, smaller proteins able to pack DNA into tiny sperm. When a man has unexplained infertility, the problem is often with retained histones. The sperm count can be normal, the sperm have normal motility, and yet because the histones are in the wrong location, the couple has trouble conceiving.
Until now, research has produced conflicting results about where these histones are located. Because of the confusion of discrepant data, the burden of assisted-reproductive technologies has continued to fall on women. Even if the male has the issue, the female partner goes through hormone injections and procedures to promote a higher fertility rate.
Imagine, then, if scientists were able to use epigenetic therapies to change the levels of histones and protamines in men. With this new research, scientists are better able to closely study the mechanisms behind a mutated sperm’s trajectory, which opens the door to potential therapeutic treatments. Epigenetic drugs are already being used to treat cancer and other diseases. With a clearer understanding of how a man’s epigenome affects conception and embryonic development, we have the potential to alter sperm, so these new studies may lead to a breakthrough infertility treatment.
If you’re struggling with infertility or considering a vasectomy reversal, the Center for Vasectomy Reversal is here to help. Under the direction of Dr. Joshua Green, our team provides state-of-the-art treatment for men who need a reversal of their vasectomy or have other concerns about their fertility. We accept major credit cards as well as cash and checks, and offer a payment plan for those who are unable to pay the entire fee at the time of surgery. Whether you’re ready to schedule a procedure or just want to learn more, you can contact us through our website, or call 941-894-6428 to arrange a free consultation.
If you’re about to become a new dad, you might be nervous and excited about this upcoming life change. Help ease your transition into fatherhood by stocking your new dad survival kit with these eight items.
- Diaper bag: Each parent should have their own diaper bag to make caring for the baby easy, no matter who takes a trip to the changing room. Masculine versions that resemble backpacks, tote bags, and messenger bags abound these days. Find leather, camo, and even sports-themed versions with all the compartments of a diaper bag without actually looking like one.
- Baby wipes: Keep a supply in your diaper bag, of course, but don’t underestimate the many uses for baby wipes besides dabbing a messy bottom. As a new dad, you may quickly learn you can use baby wipes to clean your hands after filling the gas tank, mop up spills in the car, shine your shoes, clean remote controls, swab your keyboard, and more! Always keep a box on hand, both at home and in the car.
- Hand sanitizer: Having a baby introduces a wide range of bodily fluids and messes into your life. While soap and water are best for washing up, hand sanitizer is useful on-the-go—especially if you run out of baby wipes.
- Books on fatherhood: It’s normal to feel overwhelmed during the first few weeks of being a dad, but thoughtful advice from parenting books can help you get used to the new norm.
- Headache medicine: Step one of dealing with a crying baby is to figure out what’s wrong. Once you meet his or her needs, the crying should stop. However, when a fussy baby gets the better of you, it’s okay to fight off headaches with over-the-counter pain relievers.
- Activities for “me time”: You and your partner will likely want to spend quality time together while the baby is sleeping, but set aside some “me time” each day to help you unwind. Have some activities on hand that you can enjoy on your own, such as audiobooks, podcasts, videogames, and TV shows.
- Earplugs: You shouldn’t always drown out the baby’s crying—after all, your partner needs help with nighttime feedings and diaper changes—but on nights when you really need some shut-eye, earplugs might be your best bet for sleeping through the night.
- Coffee: Restless nights definitely call for morning coffee. Consider treating yourself to a new coffee maker or a fancy French press in anticipation of your baby’s arrival.
If you’re considering reversing a vasectomy, fatherhood could be right around the corner. Discuss your options with Dr. Joshua Green at the Center for Vasectomy Reversal in Sarasota, FL. We can detail the reversal process and help you decide which surgical option may be right for you. Whether you’re ready to schedule your procedure, or you simply want to learn more, please schedule a free consultation with Dr. Green by calling us at 941.894.6428.
Contraception is a major component of reproductive health, which is important to both men and women. Interestingly, according to a recent survey by the Kaiser Family Foundation, both men and women believe that women feel more responsible for children and that women have more influence on a couple’s decision to have children. Half of the men surveyed said they don’t know much about contraceptive options. Why would that be? Men certainly have a stake in contraception, because pregnancy leads to paternal responsibility.
One reason men are not necessarily as involved as they should be in contraceptives is that reproductive health care services aren’t typically geared to men’s needs. Family planning services, whether at sexual health clinics, obstetricians’ offices, or hospitals, traditionally tend to focus on women. There’s not much funding for male services, and often a predominantly female staff will not have sufficient training to meet men’s needs. Of course, part of this is because women need prescriptions for contraceptives, while men can buy condoms over the counter. The only men who would typically involve their health care provider in their contraceptive choices are those who get vasectomies, and that is a one-time procedure.
Would men be willing to play a greater role when it comes to birth control? That same survey indicated that two–thirds of men would be willing to take male birth control pills, nearly half would take Depo-Provera shots, and over a third would be interested in getting a Norplant if these options were available for me. This is significant, but until science catches up with the good intentions of men, how can they be more involved in birth control?
As a start, men can educate themselves about contraception. There are websites with information about this topic, as well as reference books, so it’s easy to become informed. Men can also communicate with their partners, letting the women in their lives know that they’re interested in being more active participants in contraception and reproductive health.
Some men choose a vasectomy as a way to take charge of contraception, but sometimes circumstances change and the need arises to restore fertility. If you’re considering a vasectomy reversal, the Center for Vasectomy Reversal is here to help. Under the direction of Dr. Joshua Green, our caring and skilled team provides state-of-the-art treatment for men who need a vasectomy reversal or have other concerns about their fertility. Whether you’re ready to schedule a procedure or just have questions and want to learn more, you can contact us through our website, or call 941-894-6428 to arrange a free consultation.
A vasectomy reversal is an outpatient surgery. This means that the procedure doesn’t require an overnight stay in the hospital. Dr. Green asks his patients to arrive at the Surgery Center 90 minutes prior to the scheduled start of the operation. You’ll have the opportunity to ask any last minute questions you might have about the vasectomy reversal surgery, and you’ll discuss your options for anesthesia with the anesthesiologist.
Once the anesthesia takes effect, you won’t be aware of anything until you wake up in the recovery room. You’ll be carefully monitored by the medical staff until you can be discharged. A responsible adult should be available to drive you home or to your hotel if you’re traveling from out of town. Expect to be groggy for the rest of the day, and plan to get plenty of rest.
Patients of Dr. Green’s at the Center for Vasectomy Reversal benefit from close, personal attention, and specialized vasectomy expertise. Call (941) 894-6428 to request a consultation with Dr. Joshua Green in Sarasota.
Even if you’ve previously had children, bringing your baby home from the hospital represents a major transition in your life. Brush up on the basics of what to expect, like the sleeping habits of newborns. When you watch the featured video, you’ll learn that newborns sleep 16 to 17 hours per day. By four to six months, most babies will be sleeping through the night, and they’ll be awake more during the day.
This video offers helpful tips for regulating your baby’s sleep schedule. Put your newborn down for a nap every two hours. If you wait until your baby is already overly tired and fussy, he or she will have a harder time falling asleep.
At the Center for Vasectomy Reversal, we’re proud of all of the babies we’ve helped make possible over the years. When you’re ready to become a father, call Dr. Green at (941) 894-6428 to learn more about vasectomy reversals in Sarasota.
There’s a lot of misinformation about vasectomy reversals. Sometimes, the myths about the procedure may make men hesitant to consult a vasectomy reversal surgeon about their options. This is unfortunate since the procedure is a fairly routine surgery with a high success rate. And because it’s an outpatient surgery, men often find it convenient to fit into their busy schedules. Get the truth about vasectomy reversals before you make your decision.
Myth: Vasectomy reversals are linked to prostate cancer.
There is a persistent myth that men who undergo a vasectomy reversal are at a higher risk of getting prostate cancer. This would be alarming if it was true, but fortunately, it’s not. Numerous studies have demonstrated that there is no association between vasectomy reversals and prostate cancer.
Myth: Men stop producing sperm after a vasectomy.
Before you undergo surgery, it’s helpful to brush up on the basics of anatomy so you understand exactly what’s going to happen. Sperm is produced in the testicles. The vas deferens is the tube that carries the sperm from the testicles through the penis. During a vasectomy, the vas deferens is surgically clipped. This prevents the sperm from traveling out of the body. However, the procedure doesn’t affect the testicles at all, which means men continue to produce the same amount of sperm that they normally would. This means that reconnecting the vas deferens can be all that’s needed to restore male fertility.
Myth: Vasectomy reversals aren’t successful if it’s been too long.
It’s true that surgeons see higher success rates in patients who have the reversal within a few years of having the original surgery. But waiting longer doesn’t actually affect the success rate all that much. Even if it’s been 10 or 20 years, a reversal can be a success. The most important factor is to choose a surgeon who specializes in this procedure, and who has a great deal of experience with it.
Your best source of accurate, reliable information about the procedure is a vasectomy reversal surgeon. Talk to Dr. Joshua Green in Sarasota at the Center for Vasectomy Reversal and get the answers to your questions. New and current patients can reach us at (941) 894-6428.
With vasectomy reversal and other surgeries, it’s common to receive instructions not to eat or drink anything for a period of 8-12 hours before your surgery—including just a few sips of water. While it can be somewhat frustrating to follow this rule, the reason your doctor makes this recommendation is important.
When you are under general anesthesia or a twilight sedative, your body will not aspirate, or clear the airway of a blockage caused by saliva or food or liquids you’ve consumed. When you have food in your stomach, the risk of a blockage is higher, and you may choke during the surgery. Additionally, there may be significant post-surgical nausea if you go into surgery without an empty stomach, and that’s a complication that’s easier to prevent than it is to treat.
When you schedule your vasectomy reversal surgery with Dr. Joshua Green at the Center for Vasectomy Reversal, you can expect the highest quality of care within our state-of-the-art operating room as well as dedicated attention during your surgical consults and follow-up visits. To learn more about undergoing vasectomy reversal in Sarasota, FL, give us a call at (941) 894-6428.
Vasectomy reversal is performed using microsurgical techniques that are minimally-invasive, so they cause less trauma to the body and facilitate a faster, easier recovery. In fact, vasectomy reversals are most often performed on an outpatient basis, meaning you won’t even need to spend a full day in the hospital following your surgery. There are, however, still some side effects of surgery to consider, and the most prevalent and perhaps uncomfortable will be scrotal swelling. Swelling is a healing response in the body, so it’s a natural part of surgical recovery and shouldn’t cause alarm after your vasectomy reversal .
Swelling is the most common side effect of surgery.
Most men will experience post-op swelling in the scrotum, which may be mild or quite substantial. Generally, even significant swelling is not a sign of any problems. It is simply a natural part of the body’s healing process and will subside within a few days.
Swelling should not be accompanied by severe pain or bruising .
Some mild pain and bruising are normal, but when pain begins to feel intolerable or bruising is widespread, it is important to call your surgeon and discuss these symptoms. This is especially true if you are experiencing severe swelling with intense pain.
A cold compress will offer the most relief.
To control swelling, the best thing to do is take it easy and rest for the first full day after surgery while using a cold compress. Apply the cold compress to the scrotal area for about 20 minutes, and then wait about 40 minutes before the next application.
For expertise in vasectomy reversal, you can count on Dr. Joshua Green at the Center for Vasectomy Reversal in Sarasota. Not in Florida? No problem! We treat a high volume of out of town patients , often only requiring 2-3 days to complete the surgery and follow-up care. For more information about our services, give us a call at (941) 894-6428.
While vasectomy reversal is the most common procedure to restore fertility for men who have undergone a vasectomy, there are circumstances where it makes sense to consider other surgical alternatives, such as sperm aspiration. With sperm aspiration, sperm is directly obtained from the epididymis through a needle guided by an operating microscope. This is actually the first step in ICSI, or intracytoplasmic sperm injection, which is paired with IVF, or in-vitro fertilization. This video shows you a complete look at the ICSI procedure, which may play a role in your family planning if your partner is also experiencing fertility issues.
If you want to weigh the pros and cons of vasectomy reversal and ICSI, Dr. Green at the Center for Vasectomy Reversal can help you make your decision. You can schedule a vasectomy reversal consultation with us in Sarasota by calling (941) 894-6428, or visit our website to learn more.
Both eating disorders and infertility in men are underrecognized, yet common health concerns; incidentally, the two can go hand in hand. Eating disorders can cause lasting damage to the body and may result in infertility in men. Often, eating disorders are only associated with women, but men account for about 5-15% of anorexia and bulimia cases and 35% of binge eating disorder cases. Additionally, because these numbers are only based on reported cases, they may actually be higher—many men will suffer in silence with eating disorders. For any man struggling with an eating disorder, seeking treatment is important for many reasons, including the preservation of future fertility. Continue reading to gain a better understanding of how eating disorders can be a cause of male infertility .
Weight Changes and Sperm Quality
Being over- or underweight can have an impact on sperm count as well as sperm motility and overall sperm quality. With anorexia nervosa, men may be dangerously below a healthy weight range, and they might also utilize risky solutions to continue battling body fat, such as diet pills, which can cause further harm to sperm count and quality.
Risks of Over-Exercising
Along with undereating or uncontrollable binge eating, eating disorders may lead to over-exercising, which can further diminish sperm count due to the consistently higher temperature of the testes during exercise.
Potential Nutritional Deprivation
Even with binge eating disorder, which is characterized by binging sessions where someone will consume large quantities of food in a single sitting, malnourishment is common. That’s because the body is not getting the balanced diet it needs to stay healthy, and decreased sperm production may be one of the consequences of that nutritional deprivation.
Dr. Joshua Green at the Center for Vasectomy Reversal is dedicated to providing resources for men struggling with infertility, including those who are looking for vasectomy reversal procedures in Sarasota. To learn more about our practice , give us a call at (941) 894-6428 or visit our website.
- Sperm Retrieval
- vasectomy reversal
- Dr. Green
- sperm count
- male infertility
- medical care
- low sperm count
- male fertility testing
- sperm aspiration
- semen analysis
- post-vasectomy pain syndrome
- anti-sperm antibodies
- older dad
- general anesthesia
- gender reveal party
- post-operative infections
- baby name
- baby's first year
- fertilization process
- spinal anesthesia
- ACS Fellow
- nutrition tips
- concierge-level care
- fertility planning app
- out-of-town patients
- post-vasectomy reversal
- sperm quality
- baby registry
- surgical care
- surgical consultation process
- prostate cancer